The aim of this study was to evaluate the marginal discrepancy of electroforming copings, before and after the porcelain application, varying the cervical preparation of the crowns.Two master die were prepared with stainless steel to complete crown margin designs: chamfer and rounded shoulder.The impressions were taken with a polyvinylsiloxane by t
A systemic approach to the prevention of COVID-19 transmission in clinical settings in Nigeria
Coronavirus disease (COVID-19) is a respiratory illness currently ravaging the Charbroilers world in pandemic proportions.Its route of spread and a high degree of infectivity make it easily transmissible within health care settings.Health workers, who are at particular risk of workplace-related infection, should be familiar with and abide by intern
Systematic comparison of HIV-1 Envelope-specific IgG responses induced by different vaccination regimens: Can we steer IgG recognition towards regions of viral vulnerability?
Immunogens and Dog Beds vaccination regimens can influence patterns of immune-epitope recognition, steering them towards or away from epitopes of potential viral vulnerability.HIV-1 envelope (Env)-specific antibodies targeting variable region 2 (V2) or 3 (V3) correlated with protection during the RV144 trial, however, it was suggested that the immu
Tetraspanins as Potential Modulators of Glutamatergic Synaptic Function
Tetraspanins (Tspans) comprise a membrane protein family structurally defined by four transmembrane domains and intracellular N and C termini that is found in almost all cell types and tissues of eukaryotes.Moreover, they are involved in a bewildering multitude of diverse biological processes such as cell adhesion, motility, protein trafficking, si
Advances in physiological and clinical relevance of hiPSC-derived brain models for precision medicine pipelines
Precision, or personalized, medicine aims to stratify patients based on variable pathogenic signatures to optimize the effectiveness of disease prevention and treatment.This approach is favorable in the context of brain disorders, which are often heterogeneous in their pathophysiological features, patterns of disease progression and treatment respo